【摘要】 【目的】研究增加体育运动对原发性失眠患者过度觉醒的影响。【方法】51例来自精神科门诊的低体育运动水平原发性失眠患者,随机分为研究组(n=26)和对照组(n=25),两组均给予酒石酸唑吡坦(10 mg,qn)治疗,疗程4周,研究组给予简要的体育运动咨询以提高其体育运动水平。采用过度觉醒量表、睡前觉醒量表评估患者的过度觉醒程度,采用匹兹堡睡眠质量指数和睡眠日志评估患者睡眠情况。【结果】研究组睡前觉醒量表分(15.03±7.87 Vs 6.72±4.42)、睡眠日志的入睡潜伏期(24.73±22.94 Vs 19.04±19.15)及入睡后觉醒时间(24.07±18.22 Vs 17.24±15.44)的改善优于对照组(P<0.01)。【结论】提高体育运动水平可有效减轻原发性失眠患者入睡前过度觉醒状态,并且有利于睡眠的改善。更多还原

【Abstract】 【Objective】 To test the effect of increasing physical exercise on hyperarousal in the patients with primary insomnia.【Methods】 A total of 51 physically inactive patients with primary insomnia from psychiatric clinic department were recruited.Participants were randomly assigned to either intervention group(n = 26), consisting of medication with Zolpidem Tartrate Tablet plus four-week physical exercise counseling, or control group(n = 30), consisting of medication with Zolpidem Tartrate Tablet only. The primary outcome was self-report symptom, based on the Hyperarousal Scale(HAS), Pre-Sleep Arousal Scale(PSAS),Pittsburgh sleep quality index(PSQI) and sleep diaries(including Sleep Latency-SL, Wake after Sleep Onset-WASO, Sleep Efficiency-SE)which were evaluated on baseline and at the end of the 2nd, 4th week treatment. Continuous variables were evaluated by repeatedmeasures analyses of variance(ANOVA). 【Results】 The ANOVA showed a significant treatment group × time interaction, and time main effects for the scores of PSAS, SL and WASO in the two groups(P < 0.01). The patients in intervention group made significantly better outcomes than those in control group on the scores of PSAS [(15.03 ± 7.87) vs(6.72 ± 4.42)], SL [(24.73 ± 22.94) vs(19.04 ± 19.15)] and WASO [(24.07 ± 18.22) vs(17.24 ± 15.44)](P < 0.01). 【Conclusion】 Increasing physical exercise is effective for treating the hyperarousal of physically inactive patients with primary insomnia and is helpful to improve the sleep quality.更多还原