【摘要】 目的:探析十八反甘草药组临床应用规律。方法:检索某省级三甲医院近3年来(2009.11—2012.11)十八反甘草组应用情况,并对其进行分析、归纳和总结。结果:与甘草临床同用频率依次为海藻>醋甘遂>醋大戟>醋芫花,且海藻占八成以上,甘遂、大戟和芫花均用其醋炙品。就配比而言,除了海藻用量常超过炙甘草(常为炙甘草的2~3倍)外,醋甘遂、醋芫花和醋大戟的用量均常低于炙甘草,且均常为炙甘草用量的1/10最多见。就与甘草组十八反药组配伍的药物情况而言,与炙甘草反药组配伍前6名的药物分别为茯苓、桂枝、白芍、牡丹皮、炒桃仁和红参。结论:在十八反甘草组中,与甘草配伍应用最多的为海藻,而甘遂、大戟等的配伍在临床上均有应用,说明了十八反同方应用在临床中也是客观存在的,并非绝对的配伍禁忌。本研究将对甘草组十八反药组临床应用组方具有一定的指导意义。更多还原

【Abstract】 Objective: To analyze the clinical application regularity of Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs. Method: The application of Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs in provincial grade 3 class A hospitals in recent three years( November 2009—November 2012)were retrieved, analyzed, summarized and concluded. Result: The order of herbs with the same clinical application frequency with Glycyrrhizae Radix et Rhizoma were as follows: Sargassum > vinegar-Kansui Radix >vinegar-Spurge > vinegar-Genkwa Flos,with Sargassum accounted for over 80%. As for the ratio,except for Sargassum that was consumed more than Glycyrrhizae Radix et Rhizoma( usually two to three times of the consumption of baked Glycyrrhizae Radix et Rhizoma),all of vinegar-Kansui Radix,vinegar-Spurge and vinegarGenkwa Flos were consumed less than Glycyrrhizae Radix et Rhizoma( mostly 1 /10 of the consumption of baked Glycyrrhizae Radix et Rhizoma). Regarding comparable herbs with Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs,the top six comparable herbs with Glycyrrhizae Radix et Rhizoma group were Poria,Cinnamomi Ramulus,Paeoniae Radix Alba,Moutan Cortex,fired Persicae Semen,Ginseng Radix et Rhizoma Rubra tablets.Conclusion: In the Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs,the most frequent compatible herbs with Glycyrrhizae Radix et Rhizoma are Sargassum,which is followed by Kansui Radix and Spurge. It suggests that the application of 18 incompatible pairs in the same prescriptions is also an objective exist,instead of an absolute incompatibility. This study will provide certain significance in guiding the clinical application of Glycyrrhizae Radix et Rhizoma group in 18 incompatible pairs.更多还原