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激素替代治疗甲状腺术后甲状旁腺功能减退的研究进展

Research progress in hormone replacement therapy for hypoparathyroidism after thyroid surgery

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【作者】 潘明张轶西丁巍牛志昊陈闯张弘

【Author】 PAN Ming;ZHANG Yixi;DING Wei;NIU Zhihao;CHEN Chuang;ZHANG Hong;Department of Thyroid Surgery,the Second Affiliated Hospital,Jilin University;Department of Hepatopancreatobiliary Surgery,the Second Affiliated Hospital,Jilin University;

【机构】 吉林大学第二医院甲状腺外科吉林大学第二医院肝胆胰外科

【摘要】 甲状旁腺功能减退(Hypo PT)是甲状腺术后最常见的并发症之一。目前临床仍主要依靠钙剂和维生素D对症治疗,但存在很多问题。甲状旁腺激素(PTH)替代治疗作为一种新型的治疗方法逐渐被关注,且经过多年来的不断探索取得了较快发展。笔者从PTH替代治疗的药物、给药方式及对机体的影响等方面介绍其研究进展。

【Abstract】 Hypoparathyroidism(Hypo PT) is one of the most common complications after thyroid surgery.It still mainly relies on calcium supplements and activated vitamin D analogues as symptomatic treatment in clinical practice at present,which comes with many problems.Parathyroid hormone replacement therapy(PTH-RT) as a new treatment modality has increasingly been given attention,and has achieved rapid development after continuous ef orts for years.The authors present the research progress in PTH-RT from the aspects of drugs for PTH-RT,drug-delivery methods and physical impacts

【基金】 吉林省科学技术厅科技计划资助项目(201105104)
  • 【文献出处】 中国普通外科杂志 ,Chinese Journal of General Surgery , 编辑部邮箱 ,2015年05期
  • 【分类号】R653
  • 【被引频次】8
  • 【下载频次】311
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