【摘要】 目的探讨非肥胖2型糖尿病患者行袖状胃切除间置回肠的十二指肠空肠旁路手术后的营养状况变化。方法回顾性分析2009年3月至2011年11月期间我院收治的47例非肥胖2型糖尿病患者行袖状胃切除间置回肠的十二指肠空肠旁路手术术前及术后第6、12、24、36个月时血清铁、钙、维生素B12(Vit B12)、叶酸、白蛋白、血红蛋白、糖化血红蛋白(Hb A1c)、体质量指数(BMI)的变化情况。结果 1术前和术后不同时相各项检测指标情况:铁、白蛋白、血红蛋白及Hb A1c在术后不同时相均明显低于术前(P<0.01);钙、Vit B12、叶酸及BMI术后各时相与术前比较差异无统计学意义(P>0.05)。2术前和术后不同时相各项检测指标低于正常值的发生率:低铁及低白蛋白发生率术后各时相均明显高于术前(P<0.01);低钙、低叶酸、低Vit B12、低血红蛋白发生率术后各时相与术前比较,差异均无统计学意义(P>0.05)。结论袖状胃切除间置回肠的十二指肠空肠旁路手术治疗非肥胖2型糖尿病安全、有效。然而,术后可能出现营养物质的缺乏,对营养物质的缺乏要及时诊断和治疗,以改善患者的生活质量及预防相关的并发症发生。更多还原

【Abstract】 Objective To evaluate the changes of nutritional status following sleeve gastrectomy with ileal interposition duodenojejunal bypass operation in treatment of nonobese type 2 diabetes mellitus. Methods A total of 47 patients submitted to sleeve gastrectomy with ileal interposition duodenojejunal bypass operation from March 2009 to November 2011 in this hospital were retrospectively analyzed. Serum iron, calcium, vitamin B12, folic acid, albumin(Alb), hemoglobin(Hb), glycosylated hemoglobin(Hb A1c), and body mass index(BMI) were assessed before operation and on 6, 12, 24, and 36 months after operation. Results 1 The values of Alb, Hb, Hb A1 c, and iron after operation were significantly lower than those of the corresponding values before operation(P<0.01), the values of calcium, vitamin B12, folic acid, and BMI had no significant differences between after operation and before operation(P>0.05). 2 The incidences of the lower Alb and lower iron after operation were significantly higher than those before operation(P<0.01), the other indexes had no significant differences between after operation and before operation(P>0.05). Conclusions Sleeve gastrectomy with ileal interposition duodenojejunal bypass operation is an effective treatment of nonobese type 2 diabetes mellitus. However, nutritional deficiency is one of its side effects, which should be properly diagnosed and handled in order to improving the patient’s quality of life and preventing related complications.更多还原