【摘要】 目的探讨2型糖尿病患者尿微量白蛋白(UMA)与颈动脉内中膜厚度(IMT)的关系,研究微量白蛋白尿在2型糖尿病患者中预测大血管病变的价值。方法选取尿微量白蛋白异常的2型糖尿病患者111例,根据尿微量蛋白水平分为尿蛋白正常组64例(尿微量白蛋白<30mg/L),微量蛋白尿阳性组47例(尿微量白蛋白>30mg/L)。微量尿蛋白组又分为3个亚组,即A组19例(尿微量白蛋白30~50mg/L),B组14例(尿微量白蛋白50~100mg/L),C组14例(尿微量白蛋白100~300mg/L)。比较各组及各亚组微量尿蛋白水平及颈动脉内中膜厚度,探讨其相关关系。结果 UMA与IMT呈正相关性,尿微量白蛋白高即颈动脉内中膜厚度高。结论尿微量白蛋白与颈动脉硬化相关,尿微量白蛋白越高,与颈动脉硬化相关性越密切。尿微量白蛋白可能为2型糖尿病大血管及微血管病变的标志物。更多还原

【Abstract】 Objective Research on the relationship between microalbuminuria and carotid intima-media thickness in type 2 diabetic patient,Prediction of major vascular lesions of urinary albumin in type 2 diabetes mellituspatients value. Method Based on patients with type 2 diabetes in 111 cases. According to the microalbuminuria levels were divided into normal group 64 cases( microalbuminuria < 30 mg / L) and 47 cases of microalbuminuria group( microalbuminuria > 30 mg / L). Microalbuminuria group was divided into 3 sub groups,namely group A 19 cases( microalbuminuria 30- 50 mg / L),14 cases in B group( microalbuminuria 50- 100 mg / L),group C 14 cases with microalbuminuria 100- 300 mg / L). Comparison of groups and subgroups of microalbuminuria and carotid artery intima-media thickness,and explore its correlation. Result Microalbuminuria and carotid artery intima-media thickness process positive correlation. Conclusion Microalbuminuria may be the marker of macrovascular and microvessels disease in type2 diabetes mellitus.更多还原