【摘要】 目的 分析老年性社区获得性肺炎(CAP)的病原菌分布及药物敏感情况,为临床治疗和科学使用抗菌药物提供数据支持。方法 对2012~2014年重庆市合川区人民医院收治的165例老年性CAP患者的痰培养结果 进行回顾性统计分析。结果 共分离出细菌112株,前5位分别是肺炎克雷伯菌28株(25.0%)、大肠埃希菌17株(15.1%)、铜绿假单胞菌12株(10.7%)、肺炎链球菌11株(9.8%)、流感嗜血菌10株(8.9%)。药敏试验结果 显示,肺炎克雷伯菌、大肠埃希菌、铜绿假单胞菌、肺炎链球菌均对β-内酰胺类/β-内酰胺酶抑制剂及亚胺培南有良好敏感性,肺炎链球菌对青霉素耐药率较高。结论 老年CAP以革兰阴性杆菌感染为主,在经验选择抗生素时以含β-内酰胺酶抑制剂更多还原

【Abstract】 Objective To investigate the pathogen distribution and antibiotic sensitivity of community-acquired pneumonia(CAP) from the elderly patients in order to provide references for clinical treatment and scientific use of the antibacterial drugs.Methods A retrospective analysis was carried out on the results of sputum culture of 165 elderly with CAP in the People’s Hospital of Hechuan District from 2012 to 2014.Results Among the 112 totally-isolated strains of bacteria,the leading 5 bacteria were Klebsiella pneumoniae(28 strains,25.0%),Escherichia coli(17 strains,15.1%),Pseudomonas aeruginosa(12 strains,10.7%),Streptococcus pneumoniae(11 strains,9.8%),and Haemophilus influenzae(10 strains,8.9%).The results of drug sensitivity test showed that,K.pneumoniae,E.coli,P.aeruginosa and Str.pneumoniae had good sensitivity to beta lactam/beta lactamase inhibitor and imipenem.But most strains of Stre.pneumoniae were resistant to penicillin.Conclusion Gram-negative bacteria are the main pathogenic bacteria in CAP in the elderly.Empirical selection of antibiotics with beta lactam/beta lactamase inhibitor compound preparation is more appropriate for the treatment.更多还原