【摘要】 老年人术后认知功能障碍(postoperative cognitive dysfunction,POCD)严重地影响老年人的健康和生活,造成家庭和社会的严重负担,正日益受到人们的重视。近年来,脑MRI在检测老年人POCD中的脑结构、功能及代谢变化以及探讨其发病的神经机制方面的研究日益增多。结合多模态磁共振成像技术,能同时从细微结构、功能及代谢层面对疾病进行研究,为POCD的发病机制提供新的见解,为早期诊断治疗提供新的思路。更多还原

【Abstract】 More and more attention has been paid to post-oporative cognitive dysfunction(POCD),especially in the elderly.Postoperative cognitive dysfunction(POCD) seriously affects physical health and quality of lives in elderly,leading to serious burden on the family and society.Up to date,the etiology and pathogenesis of the post-operative cognitive dysfunction has been not clear yet.In recent years,increasing MRI researches on POCD have detected changes of structure,function and metabolism in this mental disorder.Combining multimodal MRI technology including structure,function and metabolism may provide further insights into the pathogenesis of POCD,and help towards early diagnosis and treatment on POCD.更多还原