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乏脂性皮炎病因和发病机制研究进展

Asteatotic dermatitis:etiology and pathogenesis

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【作者】 周丽娟吕中法

【Author】 ZHOU Li-juan;LYU Zhong-fa;Department of Dermatology,the Second Affiliated Hospital,Zhejiang University School of Medicine;

【机构】 浙江大学医学院附属第二医院皮肤科

【摘要】 乏脂性皮炎是一种因年龄、季节气候、洗浴习惯等因素引起皮肤屏障受破坏、脂质与汗腺分泌功能失调、经皮水分丢失过多,而出现皮肤干燥、瘙瘁、红斑、脱皮等临床表现的皮肤疾病,广泛存在于人群中。乏脂性皮炎的发病机制并不明确,过去的研究重视该病与洗浴习惯、季节和年龄、性别导致皮肤屏障破坏的关系,但近年来的研究趋向于探索该病与各种其他系统疾病、药物之间的关系。本文就乏脂性皮炎的病因和发病机制进行综述,旨在为临床诊断和治疗提供新的思路。

【Abstract】 Asteatotic dermatitis(AsD) is a common skin disease characterized by dry skin,itching,erythema,peeling and other skin lesions.It results from the damage in cutaneous barrier related to age,seasonal climate and bathing habits,and presents dysfunction of sebaceous,sweat glands and the increase of transepidermal water loss.The pathogenesis of AsD is not clear.Previous studies mainly focused on the relationship between skin barrier damage and bathing habits,age or gender.Recently,more studies focus on its relationship with other systematic diseases and drugs.This paper reviews etiology and pathogenesis of AsD to provide new ideas for the diagnosis and treatment of AsD.

  • 【文献出处】 浙江大学学报(医学版) ,Journal of Zhejiang University(Medical Sciences) , 编辑部邮箱 ,2015年04期
  • 【分类号】R758.6
  • 【下载频次】144
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