Enterovirus 71(EV71)is a major cause of hand,foot,and mouth disease(HFMD)in children and has been associated with serious nervous system symptoms and even death.The translation and synthesis of viral RNA depend on the 5'untranslated region(5′UTR)of a virus' genome.The 5′UTR of EV71 contains complicated secondary structures that have important roles in translation,virus replication,virus-host cell interaction,and other as yet unknown functions.Because of its extensive capabilities,the 5′UTR of EV71 has emerg...
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