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同型半胱氨酸对急性脑梗死诊断的临床价值
Investigate the clinical value of homocysteine diagnosis of acute cerebral infarction
【摘要】 目的:分析血浆内同型半胱氨酸(Hcy)水平及特点,探讨其与急性脑梗死之间的关系.方法:将我院接受治疗的172名急性脑梗死患者作为病例组,64名健康体检者作为对照组,使用高效液相色谱仪,经HPLC-FD法检测其血浆中的Hcy水平.结果:病例组在空腹情况下测定的平均血浆Hcy水平为(18.2±4.9)Izmol/L,而对照组测出Hcy浓度为(8.0±2.3)μmol/L,差异显著(P<0.01).结论:血浆Hcy水平升高是脑梗死的危险因素.
【Abstract】 AIM:To analyze the plasma homocysteine(Hcy)levels and characteristics aimed at exploring the relationship between Hcy and acute cerebral infarction.METHODS:172 patients with acute cerebral infarction in our hospital were considered as case group,and 64 healthy controls were regarded as control group.We detected the the plasma Hcy levels by high performance liquid chromatograph(HPLC-FD).RESULTS:Detecting the average plasma Hcy levels of the two group under limosis,the result showed that cases group was(18.2±4.9) μmol/L,while the control group was(8.0 ±2.3) μmol/L,and the difference between two group is notable(P < 0.01).CONCLUSION:Plasma Hcy levels increasing is a risk factor for cerebral infarction.
【Key words】 homocysteine; acute; cerebral infarction; chromatography; statistics;
- 【文献出处】 转化医学电子杂志 ,E-Journal of Translational Medicine , 编辑部邮箱 ,2015年02期
- 【分类号】R743.3
- 【被引频次】1
- 【下载频次】10