【摘要】 对十字花科Brassicaceae植物马卡独行菜Lepidium meyenii的干燥根茎玛咖进行化学成分研究,马卡独行菜的干燥根茎用70%提取,依次用石油醚、乙酸乙酯、正丁醇萃取,对各萃取部分采用各种柱色谱进行分离纯化,通过波谱数据分析(¹HNMR,¹³C-NMR,HRESIMS)进行结构鉴定。从各萃取部分共分离鉴定出18个化合物,包括7个生物碱,4个脂肪酸类化合物以及7个其他类化合物;分别鉴定为3-羟苄基氨基甲酸[（3-hydroxybenzyl）carbamic acid,1)],phenylmethanamine（2）,N-苄基甲醛（N-benzylformamide,3）,N-苄基甲酰胺（N-benzylacetamide,4）,pyridin-4-ylmethanamine（5）,n-（4-methoxybenzyl）aniline（6）,尿嘧啶（uracil,7）,琥珀酸（succininc acid,8）,癸二酸（decanedioic acid,9）,n-hexadecanoic acid methyl ester（10）,庚酸（heptanoic acid,11）,solerole（12）,糠酸甲酯（pyromucic acid methyl ester,13）,5-hydroxymethyl-2-furancarboxadehyde（14）,5-（methoxymsethyl）-1H-pyrrole-2-carbaldehyde（15）,1,7-二羟基-2,3,4-三甲氧基酮（1,7-dihydroxy-2,3,4-trimethoxyxanthone,16）,1,7-二羟基-3,4-二甲氧基酮（1,7-dihydroxy-3,4-dimethoxy-xanthone,17）,（+）-松脂醇[（+）-pinoresinol,18]。其中化合物1¹8均为首次从玛咖中分离得到。更多还原

【Abstract】 To study the chemical constituents of Lepidium meyenii,the air-dried rhizome of L. meyenii was extracted with 70%EtO H. The extract was condensed to a small amount of volume and extracted with petroleum ether,EtO Ac and n-BuO H,successively.The compounds were isolated and purified by column chromatography,and identified based on spectral analyses(¹H-NMR,¹³C-NMR,HRESIMS). Eighteen compounds were isolated from L. meyenii,including 7 alkaloids and 4 fatty acids and 7 other compounds. They were characterized as（ 3-hydroxybenzyl） carbamic acid（ 1）,phenylmethanamine（ 2）,N-benzylformamide（ 3）,N-benzylacetamide（ 4）,pyridin-4-ylmethanamine（ 5）,n-（ 4-methoxybenzyl） aniline（ 6）,uracil（ 7）,succininc acid（ 8）,decanedioic acid（ 9）,n-hexadecanoic acid methyl ester（ 10）,heptanoic acid（ 11）,solerole（ 12）,pyromucic acid methyl ester（ 13）,5-hydroxymethyl-2-furancarboxadehyde（ 14）,5-（ methoxymethyl）-1H-pyrrole-2-carbaldehyde（ 15）,1,7-dihydroxy-2,3,4-trimethoxyxanthone（ 16）,1,7-dihydroxy-3,4- dimethoxy-xanthone（ 17）,（ +）-pinoresinol（ 18）. Meanwhile,compounds 1-18 were obtained from L. meyenii for the first time.更多还原