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植物多酚干预脂质代谢紊乱作用机制研究进展

Review: plant polyphenols modulate lipid metabolism and related molecular mechanism

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【作者】 代燕丽邹宇晓刘凡李红枝

【Author】 DAI Yan-li;ZOU Yu-xiao;LIU Fan;LI Hong-zhi;School of Traditional Chinese Medicine,Guangdong Pharmaceutical University;Sericultural & Agri-Food Research Institute Guangdong Academy of Agricultural Sciences / Key Laboratory of Functional Foods,Ministry of Agriculture / Guangdong Key Laboratory of Agricultural Products Processing;

【机构】 广东药学院中药学院广东省农业科学院蚕业与农产品加工研究所农业部功能食品重点实验室广东省农产品加工重点实验室

【摘要】 脂质代谢紊乱是诱发肥胖症、高脂血症和2型糖尿病等慢性代谢疾病的重要危险因素,也是代谢综合症等慢性疾病预防的关键目标。植物多酚以多种方式参与调控机体的胆固醇吸收、甘油三酯合成和分泌以及血浆低密度脂蛋白氧化等生理进程,在维持或改善机体脂质代谢平衡中发挥着重要作用。该文就近年来植物多酚在预防和改善脂质代谢紊乱及其相关的作用机制进行综述。

【Abstract】 Lipid metabolism disorder is an important risk factor to obesity,hyperlipidemia and type 2 diabetes as well as other chronic metabolic disease. It is also a key target in preventing metabolic syndrome,chronic disease prevention. Plant polyphenol plays an important role in maintaining or improving lipid profile in a variety of ways. including regulating cholesterol absorption,inhibiting synthesis and secretion of triglyceride,and lowering plasma low density lipoprotein oxidation,etc. The purpose of this article is to review the lipid regulation effects of plant polyphenols and its related mechanisms.

【基金】 国家“十二五”科技支撑计划项目(2012-BAD36B07);广州市科技计划项目(2014J4500036);公益性行业(农业)科研专项(201403064);现代农业产业技术体系建设专项(CARS-22);广州市珠江科技新星专项(2013087)
  • 【文献出处】 中国中药杂志 ,China Journal of Chinese Materia Medica , 编辑部邮箱 ,2015年21期
  • 【分类号】R285
  • 【被引频次】19
  • 【下载频次】859
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