【摘要】 目的:研究石家庄市区户籍人口2012年恶性肿瘤发病情况。方法:2012年石家庄市区237万户籍人口医疗保险覆盖率达99%以上。将2012年1月1日至12月31日于石家庄市医保中心首次报销的住院恶性肿瘤个案经与医院数据核对后作为分子,市公安局2012年中户籍人口数作为分母,计算发病率,分析性别、年龄别和部位别肿瘤的发病特点。结果:2012年石家庄市区户籍人口恶性肿瘤粗发病率为237.53/10万,中国人口年龄调整发病率(中调率)为129.86/10万,世界人口年龄调整发病率(世调率)为167.71/10万。发病率随年龄增加而增加,男女均于75~79岁组达到高峰,分别为1 729.42/10万和867.35/10万。男性前10位的恶性肿瘤依次为肺癌、胃癌、结直肠癌、肝癌、食管癌、肾癌、前列腺癌、白血病、膀胱癌、淋巴瘤;女性分别为乳腺癌、肺癌、结直肠癌、胃癌、宫颈癌、子宫体癌、卵巢癌、淋巴瘤、食管癌及肝癌。石家庄市区户籍人口男性恶性肿瘤的粗发病率、世调率分别为269.05/10万、187.52/10万,女性分别为207.57/10万、150.44/10万。与全国31个城市2009年的世调率相比,男性肺癌、胃癌、结直肠癌与全国水平相近,女性乳腺癌高于全国水平;与北京市相比,石家庄市区男性胃癌、食管癌世调率分别约为北京市男性的2倍,但北京市男性胰腺癌、前列腺癌,女性甲状腺癌的世调率分别是石家庄市区的2倍。结论:石家庄市区户籍人口2012年主要恶性肿瘤如肺癌、胃癌、结直肠癌、乳腺癌的世调率与全国31个城市2009年的水平相当;与北京市相比,食管癌、胃癌高发,但甲状腺癌、前列腺癌、胰腺癌低发。更多还原

【Abstract】 Objective: To study the incidence rates of cancer in the urban area of Shijiazhuang city, China in 2012 based on the data of 2,374,827 registered residents. Methods: The incidence of diagnosed cancer cases in 2012 was obtained from the hospital reimbursement database of the medical insurance center of the city by retrieving the records on first-time reimbursement applications for the hospitalization of tumor patients from January 1 to December 31 in 2012. Population census data was obtained from the Population Department of the Shijiazhuang Public Security Bureau. The site-specific and sex-specific age-adjusted incidence rates were calculated. Results: The overall incidence rate, the age-adjusted rate of the Chinese population(ASRC), and the age-adjusted rate of the world population(ASRW) for both men and women were 237.53, 129.86, and 167.71 per 100,000 individuals, respectively. The incidence rate increased with age and peaked in the 75-79 years age groups of men and women at 1,729.42 and 867.35 per 100,000 individuals, respectively. The top ten most frequently diagnosed cancers in males were lung, stomach, colorectal, liver, esophagus,kidney, prostate, leukemia, bladder, as well as lymphoma, whereas those in females were the breast, lung, colorectal, stomach, cervical,uterine body, ovary, lymphoma, esophageal, and liver cancers. The incidence rate and ASRW of all cancers combined in men were269.05 and 187.52 per 100,000 individuals, whereas those for women were 207.57 and 150.44 per 100 000 individuals, respectively.Compared with the average incidence rates of 31 Chinese cities in 2009, the ASRW of lung, stomach, and colorectal cancers in males from Shijiazhuang was nearly equal to the national level; however, the ASRW of breast cancer in females from Shijiazhuang was higher than the national level. When the incidence rates of Shijiazhuang in 2012 were compared with those of Beijing in 2009, the ASRW of stomach and esophageal cancers in men of Shijiazhuang was twice that of the same cancers in Beijing. However, the same parameters for the pancreatic and prostate cancers in men, as well as the thyroid and uterine body cancers in women of Beijing, were twice the values for Shijiazhuang. Conclusion: The ASRWs of the major types of cancer, such as the lung, stomach, colorectal, and breast cancers, in urban Shijiazhuang in 2012 were identical to those of the 31 Chinese cities in 2009. Compared with Beijing, the incidence rates of pancreatic, prostate, and thyroid cancers were significantly higher in Shijiazhuang, whereas those of esophageal and stomach cancers were significantly lower.更多还原