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氮杂糖类免疫抑制剂的研究进展
Recent advances in iminosugars as immunosuppressants
【摘要】 氮杂糖作为最重要的糖模拟物之一具有多种重要的生物活性和潜在的应用价值。本文就近年来氮杂糖类免疫抑制剂的研究进行综述,主要从合成方法和免疫抑制活性评价两方面进行介绍。
【Abstract】 Iminosugars,as an extremely interesting and versatile class of carbohydrate mimics,possess various biological activities and application value. This review w ill describe the recent advances in the field of iminosugars as immunosuppressive agents,and both chemical and biological aspects concerning their preparation and / or occurrence in nature as w ell as their immunosuppressive properties w ill be discussed.
【关键词】 氮杂糖;
免疫抑制;
化学合成;
构效关系;
【Key words】 iminosugar; immunosuppressant; chemical synthesis; structure-activity relationships;
【Key words】 iminosugar; immunosuppressant; chemical synthesis; structure-activity relationships;
【基金】 国家自然科学基金重大研究计划项目(91213301)
- 【文献出处】 中国药物化学杂志 ,Chinese Journal of Medicinal Chemistry , 编辑部邮箱 ,2015年05期
- 【分类号】R977
- 【被引频次】1
- 【下载频次】361