【摘要】 目的 分析药剂科在医院合理使用中西药物联合治疗消化性疾病中的作用。方法 选择2011年1月至2013年1月在新疆维吾尔自治区人民医院接受治疗的、符合纳入标准的消化性疾病患者300例,按照随机数字表法将患者分为对照组(149例)与观察组(151例)。对照组患者采用常规中西药联合治疗,本院药剂科工作人员不给予干预,观察组患者在进行中西药物联合治疗的同时,药剂科相关工作人员积极地参与其中,协助临床医师进行临床用药。治疗3个月后,对2组患者进行疗效评价。结果 观察组中西药物联合治疗的总有效率,适应性、药物剂量和给药方式合理性、不良反应、联合用药的合理性、用药期间的治疗费用及显效时间均明显优于对照组[总有效率:94.0%(142/151)比77.9%(116/49),适应性:合理80.8%(122/151)比65.1%(97/149)、基本合理19.2%(29/151)比26.2%(39/149)、不合理0.0%(0/151)比8.7%(13/149),药物剂量和给药方式合理性:合理65.6%(99/151)比59.7%(89/149),不良反应:合理74.8%(113/151)比51.0%(76/149)、基本合理25.2%(38/151)比14.8%(22/149)、不合理0.0%(0/151)比34.2%(51/149);联合用药合理性:72.2%%(109/151)比61.9%(92/149);用药期间的治疗费用:(1 252±414)元比(2 070±339)元;显效时间:(48±8)d1比(58±10)d],差异均有统计学意义(均P<0.05)结论 药剂科积极参与中西药物联合应用的用药管理,可以更好地促进临床用药的合理性。更多还原

【Abstract】 Objective To analyze the value of pharmacy for rational use of Chinese and western medicine combination therapy treating digestive diseases.Methods Totally 300 patients with digestive diseases from January 2011 to January 2013 were randomly divided into control group(149 cases) and observation group(151 cases).Control group was given conventional combination therapy of Chinese anil western medicine without intervene from pharmacy;observation group was given additional intervene from pharmacy to assist the medication.After 3 months of treatment,the curative effect was evaluated between the two groups.Results The total efficiency,adaptability,reasonability of dosage and administration mode,adverse reactions,reasonability of drug combination,treatment cost and effective time in observation group were better than those in control group[total efficiency:94.0%(142/151) vs 76.8%(116/149);adaptability:reasonable 80.8%(122/151) vs65.1%(97/149),basically reasonable 19.2%(29/151) vs 26.2%(39/149),unreasonable 0.0%(0/151)vs 8.7%(13/149);reasonability of drug dosage and administration mode;65.6%(99/151) vs 59.7%(89/149);adverse reactions:reasonable 74.8%(113/151) vs51.0%(76/149),basically reasonable 25.2%(38/151) vs 14.8%(22/149),unreasonable 0.0%(0/151) vs 34.2%(51/149);reasonability of drug combination;72.2%(109/151) vs 60.9%(92/149);treatment cost;(1 252 ±414) yuan vs(2 070 ±339) yuan;effectivetime;(48 ±8) d vs(58 ± 10) d](P < 0.05).Conclusion Active involvement of pharmacy in medication management of Chinese and western medicine combination can promote rational clinical use of drugs.更多还原