【摘要】 目的:探讨责任药师在静脉药物配置中心(PIVAS)不合理医嘱干预中的作用,促进临床合理用药。方法:回顾性分析我院PIVAS 2012年1-6月501 115份医嘱及建立责任药师制度并进行干预后的2013年7-12月499 189份医嘱,对不合理医嘱进行整理分类和归纳分析。结果:干预前不合理医嘱共918份(0.183 2%),干预后不合理医嘱下降为448份(0.089 7%)。其中,溶剂选择不合理医嘱由134份(0.026 7%)下降为69份(0.013 8%),溶剂体积不合理医嘱由435份(0.086 8%)下降为206份(0.041 3%),给药剂量不合理医嘱由241份(0.048 1%)下降为117份(0.023 4%),配伍不合理医嘱由51份(0.010 2%)下降为28份(0.005 6%),给药频次不合理医嘱由17份(0.003 4%)下降为2份(0.000 4%)。结论:责任药师干预静脉用药不合理医嘱效果明显,提高了临床合理用药水平,保障了患者用药安全。更多还原

【Abstract】 OBJECTIVE:To probe the role of responsible pharmacist on irrational medical order intervention in Pharmacy Intravenous Admixture Service(PIVAS),and to improve rational drug use in our hospital. METHODS:501 115 medical orders from PIVAS of our hospital during Jan.-Jun. 2012 were analyzed retrospectively. Irrational medical orders of 499 189 medical orders during Jul.-Dec. 2013 were classified and summarized after the establishment of responsible pharmacists system and pharmacist intervention. RESULTS:The number of irrational medical orders was 918(0.183 2%),and decreased to 448(0.089 7%)after intervention. Irrational medical orders of solvent selection reduced from 134(0.026 7%)to 69(0.013 8%);irrational medical orders of solvent volume reduced from 435(0.086 8%)to 206(0.041 3%);irrational medical orders of drug dosage reduced from 241(0.0481%)to 117(0.023 4%);irrational medical orders of drug compatibility reduced from 51(0.010 2%)to 28(0.005 6%);irrational medical orders of dosing frequency reduced from 17(0.003 4%)to 2(0.000 4%). CONCLUSIONS:What responsible pharmacists intervened in the irrational doctor’s orders of intravenous drip was effective and feasible in PIVAS,improved rational drug use and guaranteed the safety of drug use.更多还原