【摘要】 目的:探讨持续性心房颤动(房颤)对原发性高血压患者血压昼夜节律变化的影响。方法:选取2013-01至2014-01我院就诊患者173例,将其分为原发性高血压组(高血压组,n=88),持续性房颤合并原发性高血压组(房颤合并高血压组,n=85例)。分析所有患者基线资料,并用Logistic回归分析影响持续性房颤合并原发性高血压患者的危险因素。结果:与高血压组比较,房颤合并高血压组白天平均舒张压、白天最小收缩压、白天最小舒张压、24 h平均舒张压均显著降低,夜间最大收缩压显著升高及舒张压反杓型比例显著升高(P均<0.05);两组白天平均收缩压、白天最大收缩压、白天最大舒张压、24 h平均收缩压、夜间平均收缩压、夜间平均舒张压、夜间最大舒张压、夜间最小收缩压、夜间最小舒张压及收缩压反杓型比例差异无统计学意义(P均>0.05)。多因素Logistic回归分析显示,夜间最大收缩压与持续性房颤合并高血压显著相关(比值比=1.038,95%可信区间:1.014~1.062,P<0.01)。结论:持续性房颤可导致原发性高血压患者白天血压显著下降,而夜间血压下降不明显。更多还原

【Abstract】 Objective:To explore the effect of persistent atrial fibrillation(AF) on circadian rhythm of blood pressure(BP) in patients with essential hypertension(EH).Methods:A total of 173 EH patients treated in Gansu Provincial Hospital from 2013-02 to 2014-01 were studied.The patients were divided into 2 groups:EH group,n=88 and Persistent AF combining EH group,n=85.The baseline information was studied and the risk factors of persistent AF combining EH were investigated by multivariate logistic regression analysis.Results:Compared with EH group,the Persistent AF combining EH group showed decreased average daytime DBP,minimum daytime SBP,minimum daytime DBP and the average 24-hour DBP,while increased maximum nighttime SBP and the percentage of reverse dipper in DBP,all P<0.05.There were no significant differences for the average of daytime SBP,maximum daytime SBP,maximum daytime DBP,the average 24-hour SBP,average nighttime SBP,average nighttime DBP,maximum nighttime DBP,minimum nighttime SBP,minimum nighttime DBP and the percentage of reverse dipper in SBP between 2 groups,all P>0.05.Multivariate logistic regression analysis indicated that the maximum nighttime SBP was obviously related to persistent AF combining EH(OR= 1.038,95 CI 1.014-1.062,P=0.001).Conclusion:Persistent AF may incur daytime BP dropping,such change was not obviously observed for nighttime BP in EH patients.更多还原