【摘要】 目的探讨食管癌术前半量放疗的临床效果。方法选取本院肿瘤科2012年4月~2013年4月收治的80例食管癌患者作为研究对象,其中可采取直接手术的40例设为对照组,40例需术前半量放疗再行手术的设为观察组。比较两组的临床总切除术率、根除术切除率、区域淋巴结转移率、断端残癌阳性率及随访1年生存率,观察相关并发症发生的情况。结果观察组的临床总切除术率、根除术切除率和随访1年生存率明显高于对照组,区域淋巴结转移率和断端残癌阳性率明显低于对照组,差异有统计学意义(P<0.05);观察组的总并发症发生率为10.0%,明显低于对照组的15.0%,差异有统计学意义(P<0.05)。结论食管癌术前行半量放疗,可改善患者的生活质量,延长生存期,减少转移和复发,延长远期生存率,对保障患者预后有非常重要的意义。更多还原

【Abstract】 Objective To explore the application of half-dose radiotherapy in the pre-operation of esophagus cancer.Methods 80 patients with esophagus cancer treated admitted into Department of Oncology in our hospital from April2012 to April 2013 were selected,of whom,40 cases taken with direct operation for treatment were as control group,40 cases taken with half-dose radiotherapy in the pre-operation were as observation group.The total clinical resection rate,eradicate resection rate,regional lymph node metastasis rate,residual stump positive rate of cancer,follow-up for 1-year survival rate between the two groups was compared,related complications were recorded. Results The total clinical resection rate,eradicate resection rate,follow-up for 1-year survival rate in observation group was higher than that in control group,regional lymph node metastasis rate and residual stump positive rate of cancer was lower than that in control group,the difference was significant(P<0.05).The incidence of complication in observation group was 10.0%,lower than15.0% in control group,the difference was significant(P<0.05). Conclusion Half-dose radiotherapy in the pre-operation of esophagus cancer can improve living quality,prolong lifetime,reduce metastasis and recurrence,and lengthen long-term survival rate,which all have important significances in guaranteeing patient′s prognosis.更多还原