【摘要】 目的:研究补充维生素D对于游泳运动员上呼吸道感染发病次数的影响并探讨其免疫学机制。方法:研究对象:16名专业游泳运动员,随机分为两组:维生素D胶囊补充组和空白对照组,每组8人。在饮食和作息时间基本一致的情况下,补充组口服维生素D胶囊,对照组不补充,观察两组运动员生理机能的变化情况。结果:1)两组在实验前血清中25-(OH)D3含量都低于健康标准,补充组口服维生素D胶囊3个月后血清中25-(OH)D3升至正常值,对照组仍偏低;2)补充组外周血淋巴细胞Th/Ts比值和NK细胞数高于对照组,有显著性差异(P<0.05);3)补充组外周血IgA水平高于对照组,有显著性差异(P<0.05);4)补充组冬训期间感冒次数显著少于对照组,有显著性差异(P<0.05)。结论:补充维生素D对于降低冬训期间游泳运动员上呼吸道感染发病次数有良好的效果,在正常范围内提高Th/Ts比值,NK细胞数以及IgA水平可能是其作用机理,有待进一步的实验证明。更多还原

【Abstract】 Objective:To study the effect of Vtiamin D supplements on number of swimmers upper respiratory tract infection and discuss its immunological mechanism.Methods:16professional swimmers were randomly divided into two groups:Vitamin D capsules supplement group and control group,each group of 8people.In the case of diet and daily routine are basically the same,supplement group took Vitamin D capsules,control groups did’t add,observing two groups of athletes’ physiological function change.Results:1)the 25-(OH)D3content in serum of two groups is below health standard before experiment,the 25-(OH)D3in serum for supplement Vitamin D capsule group increases to normal level after three months,while the the25-(OH)D3in serum of control group is still lower.2)The ratio of Th/Ts and NK lymphocytes in peripheral blood cell number for supplement group is higher than control group,there is significant difference(P<0.05).3)The level of IgA in peripheral blood cell for supplement group is higher than that of control group,there was significant difference(P<0.05);4)The frequency of catching cold for supplement group during the winter training is significantly less than that in the control group.There is a significant difference(P<0.05).Conclusion:There is good effect to supple Vitamin D for reducing the number of swimmers upper respiratory tract infection during winter training.The mechanism is to increase the ratio of Th/Ts,NK cell and IgA level in the normal range,but needs further tested.更多还原