Objective To explore morphological changes of bone in the progress of coal-burning fluorosis in rats.Methods Rat coal burning fluorosis model was established under low-protein and low calcium; the contents of 24-hour urinary fluoride,bone fluoride,dental fluorosis were determined to judge the degree of the injury; bone mineral density of femur and tibia was determined using X-ray absorptiometry; morphological changes of femur cancellous bone ultrastructure was observed with scanning electron microscope and ...