【摘要】 目的探讨磁共振-经直肠超声(MRI-TRUS)融合成像引导下靶向穿刺活检在前列腺癌诊断中的应用价值。方法所有患者先行融合成像引导下靶向穿刺(TB)2针,再进行系统性穿刺活检(SB)12针。结果入组首次活检患者共55例。TB前列腺癌(PCa)检出率(49.1%,27/55)、SB前列腺癌检出率(43.6%,24/55)、联合TB与SB PCa检出率56.4%(31/55)(P>0.05)。TB检出的Gleason≥7分PCa占其检出的总PCa 88.9%(24/27),SB检出的Gleason≥7分PCa占其检出的总PCa 62.5%(15/24)(P<0.05)。TB单针阳性率43.6%,SB单针阳性率17.1%(P<0.01)。结论 MRI-TRUS融合成像引导下前列腺靶向穿刺活检可检出更多的高级别PCa、单针阳性率较高,可显著减少穿刺针数。更多还原

【Abstract】 Objective To investigate the value of MRI-TRUS image fusion guided targeted prostate biopsy for the diagnosis of prostate carcinoma.Methods Each patient has suspicious lesions on T2,DWI or ADC map using a 3-T MRI system.Two-core MRI-TRUS image fusion guided lesion targeted biopsy(TB)were performed by one operator,and 12-core systematic biopsy(SB)were performed by another operator who was blind to MRI results.Results Among 55 patients,there was not significant difference of detective rate for PCa between TB(49.1%,27/55)and SB(43.6%,24/55)(P>0.05).High level Gleason score(GS≥7)PCa was found more in TB than SB,88.9%(24/27)of men with PCa on TB were high level Gleason score compared to 62.5%(15/24)on TB(P<0.05).Positive rate per core was higher for TB(43.6%)than SB(17.1%)(P<0.01).Conclusions The total PCa detection rate was not significant difference between TB and SB.TB can find more high level Gleason score patients than SB and remarkably reduce biopsy cores.更多还原