【摘要】 目的评估二维斑点追踪技术在定量评价房间隔缺损患者封堵术前、后左室扭转运动中的临床价值。方法连续入选拟行介入封堵术的房间隔缺损患者30例为病例组(ASD组),获得封堵术前、术后2d及术后6个月左室节段室壁最大旋转角度、左室整体最大扭转角度,同期选择性别及年龄相匹配的健康人30例为对照组,进行统计分析。结果 (1)ASD组后壁旋转角度峰值术前高于对照组(P<0.05),其余各节段均低于对照组(P<0.05),后壁术后2d减低并接近于对照组(P<0.05),前壁、侧壁术后2d较术前增高并接近于对照组(P<0.05),前间隔、下壁、中后间隔术直至术后6个月增高并接近对照组(P<0.05)。(2)ASD组术前左室心尖水平各节段的旋转角度峰值均高于对照组(P<0.05),直至术后6个月减低并接近于对照组(P<0.05)。(3)ASD组左室整体最大扭转角度术前小于对照组(P<0.05),术后2d即增高并接近于对照组(P<0.05)。结论二维斑点追踪技术可以早期定量评价房间隔缺损患者介入封堵术前、后左室扭转运动的变化。更多还原

【Abstract】 Objective To evaluated clinical value of two-dimensional speckle-tracking imaging(2D-STI)for the left ventricular(LV)torsion in patients with atrial septal defect(ASD)before and after the transcatheter closure.Methods Thirty patients with atrial septal defect were enrolled as a patient group and 30 cases of healthy people were selected as the control group.Get the peak rotation and the peak value of torsion angle at before and after the transcatheter closure.Then those dates were analyzed.Results(1)The peak rotation angle of posterior wall(PW)of LV at basal short axis level in ASD increased compared with control group before transcatheter closure(P<0.05)and they decreased to normal level 2-days after the transcatheter closure(P<0.05).Compared with control group,the peak values of rotation angle of other segments except for PW in ASD decreased(P<0.05).The peak rotation angle of anterior wall and laterior wall increased to normal level after 2-days undergoing transcatheter closure(P<0.05).The peak rotation angle of anterior septum,inferior wall and mid-posterior septum in ASD increased to normal level until 6-months after the undergoing transcatheter closure(P<0.05).(2)The peak rotation angle of LV at apical level short axis in ASD were higher than control group(P<0.05).These parameters decreased to normal level until 6-months after the transcatheter closure(P<0.05).(3)The peak value of torsion angle of the global LV in ASD lower than those in control group groups(P<0.05).Those parameters increased to normal level 2-days after the transcatheter closure(P<0.05).Conclusions 2D-STI can quantitative evaluate left ventricular torsion in patients with atrial septal defects before and after the transcatheter closure.更多还原