【摘要】 目的:了解福建省艾滋病病毒(HIV)感染孕产妇分娩的婴儿HIV感染与保健状况,为预防艾滋病母婴传播工作提供依据。方法:对福建省艾滋病抗体阳性孕产妇所生婴儿状况进行分析,对47例进行抗体检测的婴儿行病例对照研究。结果:161例HIV阳性孕妇所生的婴儿中失访20例,死亡14例,存活128例(其中双胞胎1例)。存活的128例婴儿中自愿接受HIV抗体检测并确认实验的有47例,检测率36.72%。12例婴儿HIV抗体检测结果为阳性,实施干预后其中5例婴儿HIV抗体检测结果由阳性转变为阴性,7例婴儿至生后18个月HIV抗体检测仍为阳性,占受检人数的14.89%。分娩方式为婴儿HIV检测结果阳性的影响因素,即剖宫产发生婴儿HIV阳性的危险度是顺产的0.1倍。结论:加大健康教育力度,采取预防艾滋病母婴传播综合干预措施是落实HIV感染者婴儿保健工作的重要前提。更多还原

【Abstract】 Objective: To understand HIV infection and health care situation among the infants by HIV- infected mothers in Fujian province,provide a basis for preventing mother- to- child transmission of AIDS. Methods: The infants born by the mothers with positive HIV antibody in Fujian province were analyzed,a case- control study was conducted among 47 infants receiving HIV antibody test. Results: Among the infants born by 161 mothers with positive HIV antibody,20 infants were lost to follow- up,14 infants died,128 infants were alive( including twin). Among 128 alive infants,17 infants voluntarily received HIV antibody examination and confirmation experiment,the detection rate was 36. 72%. Twelve infants were found with positive HIV antibody,after intervention,HIV antibody among five infants changed to negative,the other seven infants were still found with positive HIV antibody until 18 months after birth,accounting for14. 89%. Delivery modes were influencing factors of positive HIV among the infants,the risk of positive HIV among the infants born by cesarean section was 1 /10 of that by vaginal delivery. Conclusion: Strengthening health education and adopting comprehensive intervention measures to prevent mother- to- child transmission of AIDS are important premise for implementation of health care among HIV- infected infants.更多还原