【摘要】 目的探讨脊索瘤及侵袭性垂体腺瘤的临床特点,以提高诊断及治疗水平。方法回顾性分析2例酷似脊索瘤的侵袭性垂体腺瘤病例的临床资料,对比两者鉴别诊断要点并复习相关文献。结果 2例病例均无特异性症状,神经内镜经鼻行肿瘤部分切除,术后病理确诊为垂体腺瘤;术后随访未见肿瘤复发。结论侵袭性垂体腺瘤侵犯斜坡、鞍区时应当从影像学、垂体激素检查等方面明确诊断,提高初次诊断准确率,指导临床及早给予手术治疗。更多还原

【Abstract】 Objective To elevate diagnosis and treatment level through studying the clinical characteristics of chordoma and invasive pituitary adenoma. Methods Clinical data of 2 patients with invasive pituitary adenomas resembling chordoma were analyzed retrospectively. Essentials of differential diagnosis of the two tumors were compared and related literature was reviewed. Results No specific symptoms were found in the 2 cases. Endoscopic partial resection of tumor was achieved in both cases via nasal approach. The tumor was proven as pituitary adenoma by postoperative pathological examination. No recurrence occurred during follow-up. Conclusions Preoperative diagnosis of pituitary adenomas infiltrating clivus and sellar regions can be established through imaging examination, hormone check and so on.Improvement of initial diagnosis accuracy will facilitate early surgical treatment of the tumor.更多还原