【摘要】 目的分析妊娠特异性皮肤(SDP)患者血细胞及肝功能指标,探讨其变化规律。方法检测SDP患者(实验组)及健康孕妇各80例(对照组)的血细胞及肝功能并比较分析。结果实验组血WBC均值小于对照组,RBC及LYMPH高于对照组;生化检验ALT,GGT,Tbil,Dbil,TBA,PA,Alb高于正常组,ALP及5’-NT低于对照组,差异有统计学意义(P<0.05)。实验组WBC,RBC,NEUT异常例数低于正常组,生化GGT,ALP,5’-NT异常例数明显高于正常孕妇,异常比率的比较有统计学意义。结论 SDP患者与正常孕妇比较营养指标高,炎症程度低,肝损伤及胆汁瘀积严重,胎盘功能低下。需要进一步增加临床亚型的样本量,并应用纵向序贯的研究方法对孕期相关的指标作进一步探讨。更多还原

【Abstract】 Objective To investigate the characteristics of the alteration of the blood cells and the liver function in patients with specific dermatoses of pregnancy( SDP) and to analyze itsclinical significance. Methods Detection of the blood cells and the liver function levels in 80 patients with SDP and 80 healthy women with pregnancy were collected in the same time as controls. And then this datas comparatived. Results The mean of white blood cell count in SDP group was less than it’s in the control group,The mean of red and lymph blood cell count were higher than the control group( P < 0. 01); The levels of serum about ALT,GGT,Tbil,Dbil,TBA,PA,Alb in SDP group were respectively were obviously higher than those in the control group; The levels of serum about 5’-NT,ALP in SDP group were were less than those in the control group( P < 0. 01). Conclusion For patients with SDP compared with pregnant woman,the nutrition index is higher. The degree of inflammation is lower. the liver damage and cholestasis are more serious and the function of placenta is lower. Need longitudinal sequential method for pregnancy related indicators for further study.更多还原