【摘要】 目的:了解阿奇霉素致不良反应报告的特点,为临床有效、安全用药提供参考。方法:采用回顾性调查方法,对2005—2014年复旦大学附属金山医院(以下简称"我院")上报的50例阿奇霉素致不良反应报告进行统计分析。结果:50例使用阿奇霉素发生不良反应的患者中,成年女性居多,为27例,占54%;发生不良反应的给药方式以静脉给药为主(44例,占88%);不良反应的临床表现以皮肤及其附件损害最为常见(32例,占64%)。结论:医师、护士、患者应三方协作,加强用药观察与监测,减少不良反应的发生,保证患者用药安全、有效。更多还原

【Abstract】 OBJECTIVE: To probe into the characteristic of the adverse drug reactions( ADRs) induced by azithromycin for clinical reference of safe and effective use of drugs. METHODS: By a retrospective survey method,50 cases of azithromycin-induced ADR reports submitted by Jinshan Hospital Affiliated to Fudan University( hereinafter referred to as "our hospital") during 2005-2014 period were analyzed statistically. RESULTS: Of the total 50 ADR cases,27( 54%) were females; 44( 88%) were induced via intravenous administration; lesions of skin and its appendages were the most common clinical manifestation( 32 cases,64%). CONCLUSIONS: Physicians,nurses and patients should strengthen collaboration in monitoring drug use to reduce the incidence of ADRs and ensure patients’ safe and effective medication.更多还原