【摘要】 目的研究延迟拔除肾造瘘管及冲洗预防感染性铸型结石复发的临床效果。方法选取2012年1月~2013年12月于温岭市中医院进行治疗的48例感染性铸型结石患者为研究对象,将其随机分为对照组和观察组,每组各24例,对照组采用常规微创治疗,观察组在常规微创治疗基础上延迟拔除肾造瘘管及冲洗治疗。观察并比较两组患者治疗后不同时间的结石复发率,治疗前及治疗后不同时间的血清CysC、电解质及致炎、抑炎相关指标水平。结果观察组治疗后3、6、12个月的结石复发率分别为4.17%、4.17%及8.33%,均低于对照组(20.83%、20.83%、25.00%),差异有统计学意义(P<0.05)。观察组治疗后不同时间的血清CysC、电解质及抑炎、致炎相关指标均优于对照组,差异均有统计学意义(P<0.05)。结论延迟拔除肾造瘘管及冲洗预防感染性铸型结石复发的临床效果较好,对于结石生成及炎性状态相关指标均有着较好的控制作用。更多还原

【Abstract】 Objective To study the clinical effect of delayed extraction of nephrostomy tube and rinse in preventing the recurrence of infectious and staghom calculi.Methods From January 2012 to December 2013,in Traditional Chinese Medicine Hospital of Wenling City,48 patients with infectious and staghom calculi were selected as research object,and they were randomly divided into control group and observation group,with 24 cases in each group,the control group was given conventional minimally invasive treatment,and observation group was given delayed extraction of nephrostomy tube and rinse based on conventional minimally invasive treatmen.The calculi recurrence rates at different time after the treatment,serum CysC,electrolytes and proinflammatory,antiinflammatory related indexes before the treatment and at different time after the treatment in two groups was respectively observed and compared.Results The calculi recurrence rates of observation group at 3,6,12 month after the treatment was respectively 4.17% ,4.17% and 8.33% ,and these were lower than those in control group,the differences were statistically significant(P < 0.05).The serum CysC,electrolytes and proinflammatory,antiinflammatory related indexes levels in observation were all better than those in control group,the differences were statistically significant(P < 0.05).Conclusion The clinical effect of delayed extraction of nephrostomy tube and rinse in preventing the recurrence of infectious and staghom calculi is good,and it has better control effect for the stone formation and inflammatory state related indexes of patients.更多还原