【摘要】 目的探讨鼻内镜治疗鼻腔鼻窦内翻性乳头状瘤的临床疗效及预后的影响因素。方法将2009年6月至2013年6月泰州市人民医院收治的80例鼻腔鼻窦内翻性乳头状瘤患者依据随机数字表法分为鼻内镜组和侧切开组,各40例。鼻内镜组在鼻内镜下手术切除,侧切开组行鼻侧切开术。比较两组患者手术一般情况、术后复发率及并发症发生率,并分析患者预后复发的影响因素。结果鼻内镜组术中出血量显著少于侧切开组[(74±13)m L比(96±17)m L](P<0.01)。随访期内鼻内镜组总复发率为15.0%(6/40),低于侧切开组的35.0%(14/40),差异有统计学意义(P<0.05)。多因素分析显示,不典型增生、手术方式以及核分裂象数是影响患者复发的危险因素。结论鼻内镜治疗鼻腔鼻窦内翻性乳头状瘤术后复发率低;不典型增生、手术方式以及核分裂象数是影响患者复发的危险因素。更多还原

【Abstract】 Objective To explore the clinical effect of endoscopy in treatment with nasal sinus inverted papilloma and its prognostic factors. Methods A total of 80 cases of nasal sinus inverted papilloma treated in Taizhou City People’s Hospital from Jun. 2009 to Jun. 2013 were randomly divided into endoscopic group40 cases and side incision group 40 cases,and the general operation imformation,postoperative recurrence rate and the incidence of complications of the two groups were compared,and the factors affecting the prognosis and recurrence were analyzed. Results The amount of bleeding in endoscopic group was significantly lower than that in the side incision group[( 74 ± 13) m L vs( 96 ± 17) m L]( P < 0. 05). During the followup period total recurrence rate of the endoscopic group was 15. 0%( 6 /40),lower than the side incision group’s 35. 0%( 14 /40),the difference was statistically significant( P < 0. 05). Multivariate analysis showed that atypical hyperplasia,surgical approach and mitotic figures were the risk factors for the recurrence.Conclusion The recurrence rate of nasal endoscopic sinus inverted papilloma is low,and the atypical hyperplasia,operation mode and mitotic figures are the risk factors for the recurrence.更多还原