【摘要】 目的观察无创呼吸机治疗支气管哮喘合并肺炎的临床效果。方法选取2013年4月至2013年10月本院呼吸科住院的50例支气管哮喘合并肺炎患者为研究对象,采用随机数表法分为治疗组与对照组,每组各25例。对照组患者给予抗感染、二羟丙茶碱、甲泼尼龙琥珀酸钠、支气管扩张剂、排痰药物等对症治疗,治疗组患者在对照组基础上加用无创呼吸机辅助呼吸。观察并比较两组患者治疗前后日间、夜间症状评分,呼吸困难、咳嗽、肺部干/湿性啰音等体征消失时间,住院天数,治疗前后Pa O2、Pa CO2、Sa O2水平变化及疗效。结果治疗组患者治疗总有效率为96.0%(24/25),明显高于对照组[60.0%(15/25)],差异具有显著性(P<0.05)。治疗后两组患者日间、夜间症状评分均明显高于治疗前,且治疗组评分明显高于对照组(P<0.05)。治疗组患者呼吸困难、咳嗽、肺部干/湿性啰音等体征消失时间及住院天数均明显短于对照组,差异均具有显著性(P<0.05)。两组患者治疗后Pa O2、Sa O2水平均明显高于治疗前,Pa CO2水平低于治疗前,差异均具有显著性(P<0.05)。治疗组患者治疗后Pa O2、Sa O2水平均明显高于对照组,Pa CO2水平低于对照组,差异均具有显著性(P<0.05)。结论无创呼吸机对支气管哮喘合并肺炎患者的治疗效果显著,可明显改善患者临床症状,提高肺功能,值得临床推广应用。更多还原

【Abstract】 Objective To observe the clinical efficacy of noninvasive respirator in treating bronchial asthma combined with pneumonia. Method 50 patients with bronchial asthma combined pneumonia admitted by the hospital chose from April 2013 to October 2013 in our hospital were divided into treatment group and control group by random indication method, 25 cases in each group. Patients in control group were treated with infection resistance, diprophylline and methyl prednisolone sodium succinate, bronchodilator, sputum excretion medicine and other symptomatic treatments. Patients in treatment group were combined with assisted respiration of noninvasive respirator on the basis of control group. The symptom scores at night and in the daytime, dyspnea, cough, disappearance time for dry and moisture rales, days of hospitalization, changes in levels of Pa O2, Pa CO2 and Sa O2 levels before and after the treatment and efficacy were observed and compared. Result The total effective rate in treatment group was 96.0%(24/25), significantly higher than control group [60.0%(15/25)], the difference was significant(P < 0.05). After treatment daytime, nighttime symptom scores of the two groups were significantly higher than those before treatment, and scores of treatment group was significantly higher than that of control group(P < 0.05). Difficulty breathing, cough, lung wet rales and other signs disappeared time and days of hospitalization with the patients in treatment group after treatment were significantly shorter than control group, difference was significant(P < 0.05). The two groups of patients after treatment, Pa O2 and Sa O2 levels were significantly higher than those before treatment, the level of Pa CO2 was lower than that before treatment, the difference was significant(P < 0.05). After treatment the levels of Pa CO2 and Sa O2 in treatment group patients were significantly higher than control group, Pa CO2 levels were lower than control group, the difference was significant(P < 0.05). Conclusion Noninvasive respirator delivers significant efficacy on bronchial asthma combined pneumonia, and significantly improve the clinical symptoms of patients and lung function, worthy of popularization and applications in clinical practices.更多还原