【摘要】 目的观察儿科重症监护病房(PICU)感染病原菌分布及耐药性,指导临床合理应用抗菌药物。方法收集2014年1月至2014年6月本院PICU 70例患儿共160份感染标本,通过病原菌培养及药物敏感试验监测感染标本病原菌分布及耐药性。结果 160份送检标本经病原菌培养后96株(60.0%)呈阳性,其中革兰阴性菌46株(47.9%),革兰阳性菌35株(36.5%),真菌15株(15.6%);病原菌中大肠埃希菌、肺炎克雷伯菌等耐药性较高,革兰阴性菌大部分对亚胺培南、美罗培南较敏感,而革兰阳性菌对万古霉素和替考拉宁较敏感。结论 PICU内患儿发生细菌感染率高,影响治疗效果,临床应通过细菌耐药性监测,有针对性地使用抗菌药物,避免盲目应用,并减少抗菌药物使用,合理制订治疗方案,促进患儿康复。更多还原

【Abstract】 Objective To observe the distribution of infectious pathogens in pediatric intensive care unit(PICU), and analyze the drug resistance of pathogenic bacteria. Method Collected from January 2014 to June 2014 in our hospital PICU 70 patients were infected with a total of 160 specimens, by monitored pathogen culture and sensitivity test specimens and antibiotic resistance. Result 160 specimens after submission of pathogens cultured 96 isolates(60.0%) were positive. The gram negative bacilli was 46 isolates(47.9%), gram positive bacilli was 35 isolates(36.5%), 15(15.6%) strains of fungi. Escherichia coli and Klebsiella pneumoniae resistance were higher, the majority of gramnegative bacilli to imipenem, meropenem more sensitive, and grampositive cocci to vancomycin and teicoplanin Lanin more sensitive. Conclusion Children with high bacterial infections occurred in PICU, effective treatment, the clinical use of antibiotics should be targeted by bacterial resistance monitoring, avoid blind applications, and reduce the use of antibiotics, reasonable treatment plan, promote the rehabilitation of children.更多还原