【摘要】 目的观察阿托伐他汀对急性冠脉综合征患者炎症标志物的影响。方法将确诊急性冠脉综合征患者58例,随机分为观察组28例、对照组30例。2组患者入院后立即采取静脉血,然后观察组患者予阿托伐他汀40 mg,每天1次定时口服;对照组患者不用他汀类药物干预,其他治疗相同。第48小时、72小时后所有患者分别再次采取静脉血,行白细胞、C反应蛋白(CRP)及白介素-6(IL-6)检测。结果 58例患者白细胞、CRP及IL-6均明显升高,观察组经阿托伐他汀处理后,上述指标均明显下降(P<0.05)。结论急性冠脉综合征患者炎症水平增高,使用他汀类药物能显著降低炎症水平,缓解病情进展。更多还原

【Abstract】 Objective To observe the influence of atorvastatin on acute coronary syndrome(ACS)patients with inflammatory markers.Methods A total of 58 cases of ACS patients from the comprehensive diagnosis,were randomly divided into the observation group of 28 cases,and 30 cases of control group.The venous blood of two groups of patients immediately is taking after admission.Then the patients in the observation group were given atorvastatin 40 mg once a day orally,while patients in the control group without drug intervention of statins,other treatment is same.Forty- eighth hours,72 hours after all the patients were again take vein blood respectively.All specimens were detected for white blood cells,CRP and IL- 6 level.Results all the patients with ACS of white blood cells,CRP and IL- 6 increased significantly,after atorvastatin treatment,the above index decreased significantly(P<0.05).Conclusion The patients with ACS increased levels of inflammation,the use of statins can significantly reduce the level of inflammation,relieve the progress of this kind of patient.更多还原