【摘要】 目的研究神经内镜下经双鼻孔-蝶窦入路切除垂体瘤的手术优势。方法神经内镜辅助下经双鼻孔-蝶窦入路切除垂体瘤51例,回顾性分析患者的临床资料,总结手术疗效。结果肿瘤全切除38例(74.5%),近全切除11例(21.5%),部分切除2例(3.9%)。术后发生脑脊液漏3例(5.8%),暂时性尿崩症17例,经积极处理后均治愈。术后3个月随访无死亡病例及严重后遗症,手术时间为30 min~180 min,平均约81.4 min。随访3个月~12个月,平均6个月,原有症状均有不同程度改善。结论神经内镜经双鼻孔-蝶窦入路切除垂体瘤是一种创伤小、安全有效的治疗方法,随着术者手术技巧的熟练和经验的提高、内镜配套器械的完善,以及Surgical止血纱布等新型材料的应用,其临床应用必定会越来越广泛。更多还原

【Abstract】 Objective To study the operation advantage of the Treatment of pituitary adenoma via double nostril-transsphenoidal approach by neuroendoscopy. Methods Treatment of pituitary adenoma via double nostril-transsphenoidal approach by neuroendoscopy 51 cases,a retrospective analysis of clinical data of patients,summarize the effects of the operations. Results the tumor removal was total in 38 cases(74.5%),subtotal in 11 cases(21.5%),partial in 2 cases(3.9%). Nasal cerebrospinal fluid leaks,occurred in 3 cases(5.8%),temporary diabetes insipidus in 17 cases(33.3%),after active treatment were cured. Review of head MRI and preoperative imaging was compared,March follow-up,no deaths and serious sequelae,operation time is 30-180 minutes,average 81.4 minutes.Patients were followed up for 3 ~ 12 months,average 6 months,most symptoms were improved. Conclusion t Treatment of pituitary adenoma via double nostril-transsphenoidal approach by neuroendoscopy is a minimally invasive,safe and effective,with the improvement of operation skills of skill and experience to improve,endoscopic matching apparatus,and the application of surgical gauze for hemostasis,Treatment of pituitary adenoma via double nostril-transsphenoidal approach by neuroendoscopy will be more widely spread。更多还原