目的探讨5%米诺地尔溶液联合窄谱中波紫外线(Narrow Bound Ultra Violet B Light;NB-UVB)治疗头皮毛发区进展型白癜风的疗效。方法选择门诊就诊的129例头皮毛发区进展型白癜风患者随机分为两组,实验组65例采用5%米诺地尔溶液联合NB-UVB光疗进行治疗,对照组64例单纯采用NB-UVB光疗,两组患者治疗2个月为一个疗程,共治疗三个疗程,比较两组患者每个疗程结束后的疗效。结果实验组治疗一个疗程、二个疗程、三个疗程后的疗效均显著优于对照组,差异有统计学意义(P<0.05或0.01)。治疗期间两组患者均无明显的不良反应。结论 5%米诺地尔溶液联合NB-UVB治疗头皮毛发区进展型白癜风疗效显著,不良反应少,值得临床推广应用。
【英文摘要】
Objective To investigate efficacy of 5% minoxidil solution combined with Narrow Bound Ultra Violet B Light( NB-UVB) in the treatment of progressive leukoderma in scalp hair area. Methods 129 outpatients with progressive leukoderma were randomly divided into two groups. 65 cases in experience group were treated with 5% minoxidil solution combined with NB-UVB,while 64 cases in control group were merely given NB-UVB. With every two months were taken as a course of treatment,both groups were given three courses...