【摘要】 目的分析新生儿重症监护病房院内感染的途径、病原菌的分布以及耐药情况。方法回顾性分析新生儿重症监护病房病原学培养阳性的75例院内感染患儿的临床及实验室检验资料。结果病原学培养阳性的标本:血液39例,痰18例,导管9例,中段尿8例,分泌物1例。培养报告的病原菌:革兰阳性球菌42例,以表皮葡萄球菌为主;革兰阴性杆菌22例,以肺炎克雷伯杆菌为主;真菌11例,以白色念珠菌为主。细菌的耐药率很高,真菌耐药也逐渐出现。结论新生儿院内感染通过多种途径发生,以细菌感染为主,真菌感染呈上升趋势,病原体耐药情况严峻,需注意采取综合性预防措施,合理使用抗生素。更多还原

【Abstract】 Objective To analyze the route of nosocomial infection,distribution of pathogenic bacteria and drug resistance in neonatal intensive care unit(NICU).Methods The clinical and laboratory data of 75 positive cases with pathogens of nosocomial infection in NICU were retrospectively analyzed.Results Of 75 cases with nosocomial infection,the samples with positive pathogen cultivation were blood in 39 cases,sputum in 18 cases,endotracheal tube in 9 cases,midstream urine in 8cases,and secreta in one case.Gram-positive cocci was the most common bacteria,which accounted for 56.0%(42cases)and mainly composed by Staphylococcus epidermis.Gram-negative bacillus was found in 22 cases,of which Klebsiella pneumoniae was main bacteria.Moreover,fungi was seen in 11 cases with the major strain of Candida albicans.Fungal resistance has been appeared gradually.Conclusion Nosocomial infection of neonates takes place by multiple ways.Bacterial infection is most common,fungal infection is on the rise,and drug resistance of pathogens is in a severe situation.So more attention should be paid to taking comprehensive prevention measures and rational use of antibiotics.更多还原