【摘要】 目的了解不同血硒水平地区老年人群中血总胆固醇、维生素E、甘油三脂及高密度脂蛋白含量与血压的关系。方法在环境硒水平适宜的邛崃市和环境硒水平不足的剑阁县随机抽取各50名65岁以上无重大疾病自愿接受调查的老人,测量血压和采集静脉饿血进行检测,结果采用SPSS软件统计分析。结果老人中高血压比例在环境适宜硒水平的邛崃市为53.06%,环境低硒地区的剑阁县为48.00%。单纯型收缩期高血压比例邛崃市为22.45%、剑阁县为19.00%;单纯型舒张期高血压比例邛崃为2.04%,剑阁为0%。除甘油三脂外,两地老人的血硒、维生素E、总胆固醇和高密度脂蛋白含量均值的差异有统计学意义(P<0.01)。在高血压组老人和正常血压老人之间,血硒和血液中维生素E、甘油三脂、总胆固醇、高密度脂蛋白含量均值的差异均无统计学意义(P>0.05),血液中维生素E、总胆固醇、甘油三脂和高密度脂蛋白与血硒水平的关联性并不完全一致,高血压组老人比正常血压组老人的血液高密度脂蛋白含量与血硒之间呈负相关(r=-0.46)。结论该调查的100名老人中高血压患病比例与长期居住环境硒水平和对应的机体血硒水平的依赖性并不明显;环境硒水平不同地区老人的血液中维生素E、总胆固醇和高密度脂蛋白含量分别存在非常显著性的差异,但未见与血硒有明显的关联。高血压组老人与正常血压组老人血液中的硒、维生素E、总胆固醇、甘油三脂和高密度脂蛋白含量均无显著性差异;血液生化的四项指标均值与血硒均值间关联性不完全一致,其中在患高血压病的老人组中,血液高密度脂蛋白含量与血硒水平有更明显的负相关。更多还原

【Abstract】 Objective To investigate the relationship of blood pressure and the concentration of total cholesterol,vitamin E,triglyceride and high density lipoprotein among the elderly with different Se levels.Methods Fifty individuals with age>65years and without serious illnesses were randomly selected respectively from Qionglai city where environmental Se level was appropriate and Jiange county where the environmental Se level was insufficient.The blood pressure of the participants and the concentration of the target substance in venous blood were detected.The results were analyzed by SPSS.Results The prevalence rate of hypertension was 53.06%in Qionglai and was 48.00%in Jiange.The rate of simple systolic hypertension was 22.45%in Qionglai and was 19.00%in Jiange county.The rate of simple diastolic hypertension in Qionglai was2.04%and in Jiange was 0%.The average level of Se,vitamin E,total cholesterol and high density lipoprotein in Qionglai and Jiange was statistically difference(P<0.01),except for triglyceride.Between those with hypertension and those with normal blood pressure,the level of Se and all the metabolic indexes were not statistically different(P>0.05).The relationship between blood Se level and the concentration of the metabolic indexes was not consistent.The negative correlation was more obvious between the concentration of high density lipoprotein in blood and blood Se level for the hypertension group compared with the normal blood pressure group.Conclusion The dependency is proved to be not obvious between the prevalence rate of hypertension and Se level in blood and environment.The statistical difference exits between the environment Se level and the concentration of the metabolic indexes,but unrelated with the blood Se level.The concentration of metabolic indexes in the hypertension group and in the normal blood pressure group is not statistically different.The relationship is not consistent between blood Se level and the metabolic indexes in blood.The negative correlation is more obvious between the concentration of high density lipoprotein in blood and blood Se level in the hypertension group compared with the normal group.更多还原