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超声造影在经皮微波消融治疗肝癌术中的应用价值

Application of contrast-enhanced ultrasonography in patients with liver cancer during the operation of percutaneous microwave ablation

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【作者】 娄可新王兴田厉志洪

【Author】 LOU Kexin;WANG Xingtian;LI Zhihong;Graduate School, Xuzhou Medical College;Department of Ultrasonography, Xuzhou Central Hospital;Department of Ultrasonography, the Affiliated Hospital of Xuzhou Medical College;

【通讯作者】 王兴田;

【机构】 徐州医学院研究生学院徐州市中心医院超声科徐州医学院附属医院超声科

【摘要】 目的 评价超声造影(contrast-enhanced ultrasonography, CEUS)在经皮微波消融(pereutaneous microwave ablation, PMWA)治疗肝癌术中的应用价值。方法 100例(120个病灶)超声引导下进行肝癌微波消融术,其中50例患者(59个病灶)行超声造影引导(造影组),50例患者(61个病灶)未行超声造影引导(对照组),术后随访1个月,以原治疗病灶区域内或周边增强CT或CEUS发现病灶为肿瘤复发。结果 造影组复发率8%(4/50)低于对照组复发率22%(11/50)(χ~2=3.84,P=0.049 95);造影组瘤体灭活率93.2%(55/59)高于对照组瘤体灭活率72.1%(44/61)(χ~2=9.24,P=0.002)。结论 PMWA术中使用超声造影可以提高治疗效果,减少复发率。

【Abstract】 Objective To assess the application of contrast-enhanced ultrasonography(CEUS) in patients with liver cancer during the operation of percutaneous microwave ablation(PMWA). Methods A total of 100 patients with 120 focal liver lesions were treated with ultrasound-guided PMWA, of which 50 patients with 59 focal liver lesions performed CEUS guidance(an untrasonography group), and another 50 patients with 61 focal lesions did not underwent CEUS(the control). All patients were followed up for 1 month after treatment. Canter relapse were determined through enhanced CT or CEUS in focal lesions and surrounding areas. Results The recurrence rate of the untrasonography group was 8%(4/50), which was lower than the control 22%(11/50)(χ~2=3.84,P=0.04995). The inactivation rate of tumor was 93.2%(55/99), which was higher than the control 72.1%(44/61)(χ~2=9.24, P=0.002). Conclusion The use of CEUS in PMWA can increase efficiency and reduce relapse rate.

  • 【文献出处】 徐州医学院学报 ,Acta Academiae Medicinae Xuzhou , 编辑部邮箱 ,2015年12期
  • 【分类号】R445.1;R735.7
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