【摘要】 目的:探讨经皮冠状动脉介入治疗(PCI)术后冠心病患者负性情绪发生情况及其对预后的影响。方法:采用焦虑自评量表(SAS)和抑郁自评量表(SDS)对接受PCI手术的90例患者进行评定,按照评分结果分为单纯抑郁组(28例,占31.11%)、单纯焦虑组(22例,24.44%)、焦虑合并抑郁组(25例,27.78%)和正常组(15例)。对患者进行12个月的随访,采用Logistic回归分析主要不良心血管事件(MACE)的危险因素。结果:单纯抑郁组、单纯焦虑组、焦虑合并抑郁组患者MACE发生率显著高于正常组(42.86%比40.91%比64.00%比6.67%,P<0.05或<0.01)。焦虑合并抑郁组MACE发生率显著高于单纯焦虑组和单纯抑郁组(P均<0.05)。Logistic回归结果显示焦虑、抑郁、焦虑合并抑郁是MACE的危险因素(OR=1.49、2.16、3.28,P<0.05或<0.01)。结论:大多数PCI术后患者存在负性情绪,负性情绪是发生不良临床事件的危险因素,影响患者预后。更多还原

【Abstract】 Objective:To explore influence of negative emotions on prognosis of patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Methods:Self-rating anxiety scale(SAS)and self-rating depression scale(SDS)were used to assess 90 patients undergoing PCI.According to the score results,patients were divided into pure depression group(n=28,occupied 31.11%),pure anxiety group(n=22,24.44%),anxiety complicated depression group(n=25,27.78%)and normal group(n=15).All patients were followed up for 12 months,and Logistic regression analysis was used to analyze risk factors for major adverse cardiovascular events(MACE).Results:Incidence rates of MACE in pure depression group,pure anxiety group and anxiety complicated depression group were significantly higher than that of normal group(42.86% vs.40.91% vs.64.00% vs.6.67%,P<0.05 or <0.01),and that of anxiety complicated depression group was significantly higher than those of pure depression group and pure anxiety group(P<0.05both).Logistic regression analysis indicated that anxiety,depression,anxiety complicated depression were risk factors for MACE(OR=1.49,2.16,3.28,P<0.05or<0.01).Conclusion:Most patients undergoing coronary intervention possesses negative emotions,which are risk factors for adverse clinical events and affect their prognosis.更多还原