【摘要】 目的:探讨精浆脂蛋白(a)、锌和前列腺特异性抗原(PSA)与精液液化的关系。方法:筛选精液液化异常患者和精液液化正常男性各200例,显色法测定精浆锌离子(Zn2+),酶联免疫法测定PSA,乳胶增强免疫透射比浊法测定脂蛋白(a),对比分析两组测定结果。结果:异常组精浆Zn2+平均含量为(90.0±35.1)μg/m L,脂蛋白(a)水平为(550±250)μg/m L;正常组精浆Zn2+平均含量为(125.1±25.5)μg/m L,脂蛋白(a)水平为(301±98)μg/m L,两者差异有统计学意义(均P<0.01)。异常组精浆PSA含量为(0.81±0.21)mg/m L,正常组精浆PSA含量为(1.31±0.30)mg/m L,两者差异有统计学意义(P<0.05)。结论:精液液化异常可能与精浆脂蛋白(a)水平增高,Zn2+及PSA含量偏低有一定的相关性。更多还原

【Abstract】 Objectives: To explore the relationship of levels of seminal plasma lipoprotein( a),Zn2 + and prostate specific antigen in the semen with abnormal semen liquefaction. Methods: 200 patients with abnormal semen liquefaction and 200 men with semen liquefaction were selected. The level of seminal zinc was detected by color- developing method. The level of PSA in seminal was measured by ELISA and the lipoprotein( a) was measured by latex enhanced immunoturbidimetric assay. Results: The levels of Zn2 +in abnormal group and normal group were( 90. 0 ± 35. 1) μg / m L and( 125. 1 ± 25. 5) μg / m L respectively,with significant difference( P < 0. 01). The levels of lipoprotein( a) in abnormal group and normal group were( 550 ± 250) μg / m L and( 301 ± 98) μg / m L respectively,with significant difference( P < 0. 01). The levels of PSA in abnormal group and normal group were( 0. 81 ± 0. 21) mg/m L and( 1. 31 ± 0. 30) mg/m L respectively,with significant difference( P < 0. 05). Conclusion: The levels of seminal lipoprotein( a),Zn2 +and PSA should be taken into account in the diagnosis of male infertility caused by abnormal liquefaction.更多还原