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支原体感染与不孕症相关影响因素的研究

Study on the influencing factors of mycoplasma infection of female infertility

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【作者】 肖海燕李婧尚存莲席雅娟

【Author】 XIAO Haiyan;LI Jing;SHANG Cunlian;XI Yajuan;Department of Obstetrics and Gynecology,Longhua District People’s Hospital of Shenzhen;Clinical Laboratory,Longhua District People ’s Hospital of Shenzhen;

【机构】 深圳市龙华新区人民医院妇产科深圳市龙华新区人民医院检验科

【摘要】 目的:探索研究女性支原体感染对不孕症的具体影响。方法:选择我院收治的不孕患者240例作为研究组,同时选择在我院接受健康体检的非不孕妇女共计240例作为对照组,对两组对象进行支原体检测并对相关因素进行对比判断。结果:研究组患者的解脲支原体阳性率为36.67%,显著高于对照组研究对象的13.34%(P<0.05);原发不孕患者解脲支原体阳性率为34.29%,继发不孕患者则为39.00%,组间差异不具有统计学意义(P>0.05);不孕患者支原体对罗红霉素的耐药率高达56.25%,对强力霉素的敏感率高达87.50%,对克拉霉素的敏感率为77.92%,对氧氟沙星的敏感率为75%。结论:支原体感染与女性不孕具有极为密切的关系,其具体致病机制还需深入研究,为预防和治疗提供科学依据。

【Abstract】 Objectives: To explore the influencing factors of mycoplasma infection of female infertility. Methods: 240 infertility patients in our hospital were selected as study group and 240 cases of non- infertile women were selected as control group. Mycoplasma test on two groups was done and the relevant factors were compared. Results: The positive rate of ureaplasma urealyticum(Uu) in patients of the study group was 36. 67%,which was significantly higher than that in the control group(13. 34%)(P < 0. 05). The positive rate of Uu in primary infertility patients was 34. 29%and the positive rate of Uu in secondary infertility patients was 39%. The difference between groups was not statistically significant(P > 0. 05). Mycoplasma resistance rate of roxithromycin in infertility patients was as high as 56. 25%; the rate of susceptibility to doxycycline was as high as 87. 50%; the sensitive rate of clarithromycin was 77. 92% and the rate of susceptibility to ofloxacin was 75%. Conclusions: Mycoplasma infection is very close related to female infertility,and the specific pathogenesis needs further studied to provide scientific basis for prevention and treatment of infertility.

【基金】 广东省深圳市龙华新区科技计划项目(2013062)
  • 【文献出处】 中国性科学 ,Chinese Journal of Human Sexuality , 编辑部邮箱 ,2015年07期
  • 【分类号】R711.6
  • 【被引频次】15
  • 【下载频次】62
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