【摘要】 目的探讨64层螺旋CT脑灌注成像在急性脑缺血性疾病中的诊断价值。材料与方法20例急性脑缺血性疾病的患者行64层螺旋头颅CT平扫、CT脑灌注成像(CT perfusion,CTP)检查,将CT平扫图像与CTP图像及各参数比较,同时梗死区与周围半暗带及健侧各CTP参数比较。结果首次头颅CT平扫发现脑梗塞病灶12例,复查头颅CT检出腔隙性脑梗塞2例;CTP发现18例病灶,2例腔隙性脑梗塞CTP未见异常。在灌注异常的CTP图像中,测定病灶中央、周围区及健侧的脑血流量(CBF)、脑血容量(CBV)、对比剂平均通过时间(MTT)及达峰时间(TTP),病灶中央与周围区、病灶与健侧对比差异有统计学意义(P<0.05)。结论64层螺旋CT脑灌注成像能提高急性脑缺血性疾病病灶的检出率。分析CTP各参数可区分脑梗死区及缺血半暗带,有助于临床对治疗方案的选择及对预后的判断。更多还原

【Abstract】 Purpose To explore the value of brain perfusion with 64-slice computered tomography(CT) in Diagnosis of acute ischemic cerebrovascular diseases.Materials and Methods 20 patients diagnosed as acute ischemic cerebrovascular diseases underwent plain CT and CT perfusion(CTP).Compare plain CT with The CT perfusion parameters,then compare infarction area with ischemic penumbra and the contralateral.Results 12 cases cerebral infarcts were detected with plain CT,and another 2 cases cerebral infarcts were detected with the plain CT review.18 cases cerebral infarcts were detected CTP,and 2 cases lacunar infarction were not detected with CTP.With the CTP,detected CBF,CBV,MTT and TTP in the central and the surronding of the infarct and the contralateral,and the differences were statistically significant(P <0.05).Conclusion 64-slice CT perfusion could improve the detection rate of acute ischemic cerebrovascular diseases.CTP parameters can distinguish infarcts and ischemic penumbra,and it help Clinical choice of treatment.更多还原