【摘要】 目的了解2004-2012年丽水市急性弛缓性麻痹(AFP)病例监测系统的运行情况,分析监测质量。方法监测15岁以下AFP病例,由专业人员对病例调查、采便和随访,在省级疾控中心对粪便标本进行病毒分离和鉴定;省AFP病例专家诊断小组对每例AFP病例进行最终分类;应用SPSS13.0和AFP监测信息报告管理系统对数据进行统计分析。结果 2004-2012年共报告AFP病例81例,按15岁以下儿童数年平均报告发病率为2.10/10万,男女之比为1.79∶1;多为单侧下肢麻痹,占80.25%;3次及以上脊灰糖丸疫苗接种史者占87.65%;冬春季发病较多;共分离到4株肠道病毒,阳性率4.94%,其中非脊灰肠道病毒(NPEV)2株,脊灰病毒(PV)2株(Ⅰ+Ⅱ型),脊灰病毒阳性率为2.47%,经国家疾控中心参比实验室核实均为脊灰疫苗相关株;双份合格粪便采集率100%,粪便及时送检率95.10%,病例48 h流调率100%;监测医院漏报率为10.00%。结论丽水市AFP监测质量较高,常规免疫接种率维持较高水平,同时应采取措施控制监测漏洞。更多还原

【Abstract】 Objective To understand the status of acute flaccid paralysis(AFP) case surveillance system and analyze the monitoring quality in Lishui during 2004 to 2012. Methods We investigated and followed up the patients who were AFP under 15 years old.The fecal specimen were isolated and identified for viruses in provincial center for disease control. The expert of provincial diagnostic team make the final classification for every case. The data were analyzed by SPSS13.0. Results 81 AFP cases were reported from 2004 to 2012. The average reported incidence of children under 15 years old was 2.10/100 000, and the male to female ratio was 1.79:1. The proportion of unilateral paralysis of the legs was 80.25%. The proportion that vaccination history of the polio candy vaccine more than three times was 87.65%. The incidence was higher in winter and spring. 4 enteroviruses were isolated in total, and the positive rate is 4.94%. The non-polio enteroviruses(NPEV) were two strains and the poliovirus(PV) were two strains among them, and the positive rate of poliovirus was 2.47%. The viruses were the Polio vaccine-associated strains after the national CDC reference and laboratory verification. The rate of double adequate stool collection was 100%, the timely submission rate of stool was 95.10%, and the epidemiological survey rate of the case in 48 hours was 100%. The false negative rate of monitoring hospital was 10.00%. Conclusion The monitoring quality and the routine immunization coverage in Lishui were high. At the same time we should take measures to control monitoring loopholes.更多还原