【摘要】 目的分析山东省接种乙肝疫苗(Hepatitis B Vaccine,Hep B)后发生死亡的病例,评价Hep B安全性。方法对2006年1月-2014年2月山东省各地报告并开展调查的接种Hep B后死亡病例资料进行分析。结果报告的13例接种Hep B死亡的病例中,2例为接种Hep B导致过敏性休克而死亡,1例为接种流感疫苗(Influenza Vaccine,Inf V)导致过敏性休克而死亡,其他10例均为偶合其他疾病所致死亡,与接种Hep B无关。结论 Hep B安全性良好,偶合症是预防接种后死亡的常见类型,尸检是判断因果关联的关键措施。更多还原

【Abstract】 Objective To evaluate the safety of Hepatitis B vaccine(Hep B) by analyzing 13 dead infants after immunization.Methods We collected the reported and investigating data of dead infants after Hepatitis B vaccine in Shandong from January 2006 to February 2014. Results In 13 dead cases after Hep B, 2 cases were acute anaphylactic shock caused by Hep B, and 1 case was acute anaphylactic shock caused by influenza vaccine. Besides, other 10 cases with coupling other diseases were not related to Hep B. Conclusions Hep B is safe. Coincidental event is the most common style after the death of vaccination. Autopsy is the key measure to determine a causal association更多还原