【摘要】 目的观察复方沙棘籽油栓联合安尔碘Ⅲ型消毒剂治疗细菌性阴道病的临床疗效。方法选择临床诊断为细菌性阴道病的患者185例。按照就诊时间次序随机分为A、B、C 3组,A组口服甲硝唑联合阴道纳药复方沙棘籽油栓治疗,B组阴道纳药复方沙棘籽油栓加安尔碘Ⅲ型消毒剂消毒外阴阴道治疗,C组阴道纳药复方沙棘籽油栓加安尔碘Ⅲ型消毒剂消毒外阴阴道并口服甲硝唑。比较3组患者治疗后的临床症状、综合疗效、实验室检查、复发率及用药安全性等情况。结果 B组、C组在综合疗效有效率、改善阴道p H值、胺试验转阴率及治疗前后临床症状评分改善情况比较均优于A组,B组、C组的复发率也明显低于A组,在快速改善临床症状方面B组和C组具有治疗优势,而B组不良反应发生率低于A组和C组。结论阴道纳药复方沙棘籽油栓加安尔碘Ⅲ消毒剂消毒外阴阴道的方法可以有效治疗细菌性阴道病,在快速缓解症状、控制复发等方面值得临床推广。更多还原

【Abstract】 Objective It is to observe the clinical efficacy on bacterial vaginosis treated by Compound Hippophae Rhamnoides seed oil suppository combined with An’erdian Ⅲ disinfectant. Methods 185 patients were diagnosed with bacterial vaginosis in clinic. According to the treatment time,the patients were divided into 3 groups randomly. Group A was treated with metronidazole orally combined with putting compound Hippophae Rhamnoides seed oil suppository into vagina. Group B was treated with compound Hippophae Rhamnoides seed oil suppository into vagina and disinfecting the vagina and vulva with An’erdian Ⅲ disinfectant. Group C was treated with compound Hippophae Rhamnoides seed oil suppository into vagina,disinfecting the vagina and vulva with An’erdian Ⅲ disinfectant combined with metronidazole orally. The clinical symptoms,comprehensive therapeutic effects,laboratory examinations,the recurrence rates and drug safety of those groups were compared.Results The comprehensive therapeutic effects,improvements of vaginal p H,normal rates of ammonia transfer,and improvements of clinical symptoms after treatment in group B and C were better than that of group A. The recurrence rates of group B and C were obviously lower than that of group A. In getting faster improvements of clinical symptom group B and C were better than group C. But the rate of adverse effect of group B was lower than that of group A and C. Conclusion Putting Compound Hippophae Rhamnoides seed oil suppository into vagina and disinfecting vagina and vulva with An’erdian Ⅲdisinfectant can effectively treat for bacterial vaginosis. In order to getting symptom relieving faster and controlling the recurrence,this method should be promoted.更多还原