The properties of sarcoplasmic reticulum(SR) calcium handling are crucial for differentiation, development and maturation of cardiomyocytes, and are also the basic for cardiac contraction and heart pumping. Lots of heart diseases are related to the dysfunction of SR calcium handling. Accumulated data were amassed showing that micro RNAs(mi RNAs) participated and played important role in regulating cardiac SR calcium handling, and contributed to some heart diseases or protection of heart function. Here we ai...