Autophagy is a highly-conserved metabolic process in eukaryotes. It serves to clear damaged organelles, degrade glycogen, lipids and protein for cellular metabolic reuse, and it plays an important role in the homeostasis of cellular metabolism. Autophagic dysfunctions are often found to be involved in metabolic diseases, such as Pompe disease, obesity and neurodegenerative diseases. Here we reviewed the studies on the relationship about autophagy, metabolism and metabolic diseases in recent years.
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