Cancer stem cells(CSCs) are defined as a kind of undifferentiated cells that can self-renew and differentiate. Like normal stem cells, the CSCs also have multipotency capable of differentiating into different cancer cells with heterogeneity, and are usually resistant to the traditional drug therapies. The differences between CSCs and normal stem cells are the abnormal activation of some signal pathways and the expression of different biomarkers. Targeting the differences, scientists come up with some strate...
Antibody Therapeutics that Target Cancer Stem Cells(CSCs)—for SomeSignal Pathways and CSCs Markers本行为和发展规律,为人类攻克癌症这一难题提供了新的思路。肿瘤干细胞或称肿瘤起始细胞(tumorinitiating cell,TIC),首先是由Lapidot等[3]在对人类急性白血病细胞的研究
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