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我院912例药品不良反应报告统计分析
Statistical analysis of 912 adverse drug reaction reports in our hospital
【摘要】 目的探讨我院药品不良反应(ADR)发生的规律和特点,以促进临床合理用药。方法采用回顾性分析方法,对我院2012~2013年912例药品不良反应报告进行分类统计与分析。结果 912例ADR中,年龄大于60岁患者占31.91%,以抗菌药物诱发的ADR居多(32.02%),静脉滴注给药是引发ADR的主要途径(74.12%),最常见临床表现为皮肤及其附件损害(36.18%),绝大部分ADR经过相关处理后能够完全治愈(55.92%)或者好转(42.76%)。结论医务人员应加强药品ADR监测,密切观察患者用药后的临床表现和反应,合理指导用药,减少ADR的发生。
【Abstract】 Objective To investigate the characteristics and regularity of adverse drug reaction(ADR)in our hospital for promoting rational drug use.Methods By retrospective study,912 ADR reports in our hospital during 2012-2013 were analyzed statistically.Results Among 912 ADR cases,32.02% ADR reports were caused by antibiotics drugs,patients aged over 60occupied31.91%,and intravenous route was the major cause of ADR(74.12%).The lesion of skin and its appendants were the most common clinical manifestation of ADR(36.18%),such as erythra and pruritus.And most of them were improved(55.92%)or cured(42.76%).Conclusion Medical personnel should attach importance to supervise and report ADR,observe clinical manifestations and reaction,reduce the ADR,and promote rational drug use in the clinical work.
【Key words】 adverse drug reaction; safety; rational drug use; statistical analysis;
- 【文献出处】 西北药学杂志 ,Northwest Pharmaceutical Journal , 编辑部邮箱 ,2015年01期
- 【分类号】R95
- 【被引频次】4
- 【下载频次】84