【摘要】 目的:探讨高原移居战士负荷运动前后氧化/抗氧化状态及红益胶囊的抗氧化效果。方法:对平原入伍到海拔3 800m高原地区6~24个月健康男性战士8名,分别在服用红益胶囊前及服药5、8d检测运动前静息状态、运动后30 min时的血清8-iso PGF2α、MDA、SOD、GSH-Px水平的变化。结果:与静息状态比较,服药前、服药5、8d,运动后血清8-PGF2a、MDA水平明显增高(均P<0.01),血清SOD、GSH-Px水平明显降低(均P<0.01);与服药前运动后比较,服药后8d,运动后血清8-PGF2a、MDA水平明显降低(均P<0.01),血清SOD、GSH-Px水平明显升高(P<0.01或P<0.05)。结论:移居高原战士运动后存在明显的氧化应激,红益胶囊能明显减轻运动后氧化应激性损伤。更多还原

【Abstract】 Objective:To investigate the oxidation/antioxidation states before and after load exercise in plateau migrant sodiers and the antioxidative effect of hongyi capsules.Methods:Eight healthy male soldiers who joined the army in plain and came to plateau of 3 800 mfor 6to 24 months were enrolled.Before and 5or 8days after oral intake of hongyi capsules,serum 8-iso PGF2α,MDA,SOD and GSH-Px of all the soldiers in resting state before exercise and 30 min after exercise were examined respectively.Results:Compared with in resting state,serum 8-PGF2 aand MDA were significantly increased(P<0.01)while serum SOD and GSH-Px were significantly decreased(P <0.01)after load exercise,before and 5or8 days after oral intake of hongyi capsules.After 8days of oral intake of hongyi capsules,serum 8-iso PGF2 aand MDA were significantly lower while SOD and GSH-Px were significantly higher after load exercise compared with that before medication(P<0.01 or P<0.05).Conclusion:There is obvious oxidative stress in plateau migrants after load exercise,and hongyi capsules can significantly reduce injuries induced by oxidative stress after load exercise.更多还原