【摘要】 目的分析腹腔热灌注与静脉化疗在晚期胃肠道肿瘤治疗的效果。方法选取我院曾收治的100例晚期胃肠道肿瘤患者,将其分成对照组和观察组,对照组患者采用单纯静脉化疗,观察组患者采用腹腔热灌注联合静脉化疗,观察患者在治疗期间所出现的不良反应,并对比两组患者的治疗效果。结果患者在治疗期间,均有不同程度上出现脱发、肝损伤、消化道不适、肾功能异常等不良反应,两组无差异(P>0.05);治疗后,观察组患者的总有效率为78%,对照组患者的总有效率为46%,两组患者治疗效果差异具有统计学意义(P<0.05)。结论腹腔热灌注联合静脉化疗对晚期胃肠道肿瘤患者具有良好的治疗效果。更多还原

【Abstract】 Objective To analyze the peritoneal perfusion with intravenous chemotherapy in advanced gastrointestinal effects of cancer treatment. Methods Our hospital had treated 100 patients with advanced gastrointestinal cancer,were divided into a control group and observation group,control group were treated with intravenous chemotherapy alone,the observation group were treated with intraperitoneal hyperthermic perfusion combined with intravenous chemotherapy. Treatment adverse reactions that occurred was observed,and compared the therapeutic effect to two groups. Results The patients during treatment,there were varying degrees of hair loss,liver damage,gastrointestinal discomfort,renal dysfunction and other adverse reactions,the difference was not significantly different(P > 0.05),after treatment,the total effective rate of patients in the observation group was 78%. The total effective rate was 46% in the control group,treatment groups were significantly different(P < 0.05),with statistical significance. Conclusion Intraperitoneal hyperthermic perfusion combined with intravenous chemotherapy in patients with advanced gastrointestinal tumors with a good therapeutic effect,in future clinical applications.更多还原