目的探讨电针听宫穴和翳风穴对豚鼠听皮层葡萄糖代谢和胰岛素样生长因子-1(insulin like growth factor-1,IGF-1)表达的影响。方法将成年杂色豚鼠18只随机分为3组,电针耳穴组7只,同时电针双侧听宫和翳风穴,持续15分钟,每日1次,共7天;电针非穴位组6只,电针听宫穴靠眼侧方5mm处和翳风穴正下方5mm处,时间同电针耳穴组;对照组5只不作任何处理,常规饲养。各组完成电针后进行PET/CT扫描,获得CT、PET及两者融合图像,观察豚鼠听皮层摄取显像剂18F-脱氧葡萄糖的情况,以听皮层和小脑最大标准摄入值(standard uptake value,SUV)的比值为观察指标;采用实时荧光定量PCR技术检测豚鼠听皮层IGF-1mRNA表达。结果对照组、电针耳穴组、电针非耳穴组听皮层SUV最大值与小脑SUV最大值的比值分别为0.75±0.06、0.84±0.05和0.71±0.06,电针耳穴组高于对照组和电针非耳穴组,(分别为P=0.042,P=0.009);对照组、电针耳穴组、电针非耳穴组听皮层局部IGF-1mRNA相对表达量分别为1.34±0.24、2.03±0.36、0.92±0.23...
【英文摘要】
Objective To investigate the effects and mechanisms of electroacupuncture at Tinggong and Yifeng on the local expression of insulin like growth factor-1(IGF-1)and glucose metabolism in the auditory cortex of guinea pig.Methods Eighteen Adult pigmented guinea pigs were randomly divided into 3groups.Guinea pigs in electroacupuncture at auricular points group(EAPG,n=7)were electroacupunctured at Tinggong and Yifeng acupoints simultaneously for 15 minutes every day,and electroacupunctur lasted 7days.The electro...
| 
推荐 
点击下列相关研究机构和相关文献作者，可以直接查到这些机构和作者被《中国知识资源总库》收录的其它文献，使您全面了解该机构和该作者的研究动态和历史。
